Dead Space

Dead Space is one of my favorite video games. It's about humans vs. necromorphs(Greek for "dead forms"). In the game you play as a CEC engineer named Isaac Clarke. He volunteers for a repair mission on the USG Ishumira, a planet craker vessel. Once on board, he and the repair crew discover that everyone on the Ishumira has been killed by a disease that recombines dead tissue into disgusting beasts. One of the crew members, Kendra, is actually a government agent sent to recover an artifact called "the marker". The marker caused the disease, and she wants to bring it back to Earth. At the end of the game, Kendra dies, and the marker was destroyed. Isaac was the only survivor.